本发明提供一种检测抗蛋白酶体亚基α1‑IgG抗体的试剂盒，由抗原蛋白Proteasomesubunit alpha type 1(蛋白酶体亚基α1)、固相载体、标记抗体、抗原和抗体稀释液、样品稀释缓冲液、底物显色剂、洗涤液、标准品、阳性和阴性质控品组成。本发明试剂盒利用间接法反应原理结合磁微粒化学发光免疫分析检测待检血清中的抗蛋白酶体亚基α1‑IgG抗体。本发明首次鉴定出自身免疫性肾病综合征患者血清中针对靶抗原蛋白酶体亚基α1的自身抗体。本发明为国内外针对与蛋白酶体亚基α1和蛋白酶体亚基α1‑IgG自身抗体有关的自身免疫性肾病综合征的分子机制研究及临床诊疗提供依据。
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[8]Array to string conversion[/websites/wwwroot/www.china-mcc.com/thinkphp/library/think/Url.php:147]
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[8]Array to string conversion[/websites/wwwroot/www.china-mcc.com/thinkphp/library/think/Url.php:147]
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[ DB ] CONNECT:[ UseTime:0.001436s ] mysql:host=pc-m5epcw1px949b110u.rwlb.rds.aliyuncs.com;port=3306;dbname=yousedb;charset=utf8
[ SQL ] SHOW COLUMNS FROM `tb_para` [ RunTime:0.001587s ]
[ SQL ] SELECT * FROM `tb_para` WHERE `id` = 1 LIMIT 1 [ RunTime:0.001342s ]
[ SQL ] SHOW COLUMNS FROM `tb_tech` [ RunTime:0.001236s ]
[ SQL ] UPDATE `tb_tech` SET `hit`=`hit`+1 WHERE `id` = 863583 [ RunTime:0.001195s ]
[ SQL ] SELECT * FROM `tb_tech` WHERE `id` = 863583 LIMIT 1 [ RunTime:0.001000s ]
[ SQL ] SHOW COLUMNS FROM `tb_admin` [ RunTime:0.001113s ]
[ SQL ] SELECT `realname` FROM `tb_admin` WHERE `id` = 1 LIMIT 1 [ RunTime:0.000871s ]
[ SQL ] SHOW COLUMNS FROM `tb_category` [ RunTime:0.001027s ]
[ SQL ] SELECT * FROM `tb_category` WHERE `id` = 147 LIMIT 1 [ RunTime:0.000939s ]
[ SQL ] SELECT * FROM `tb_category` WHERE `id` = 30 LIMIT 1 [ RunTime:0.000892s ]
[ SQL ] SHOW COLUMNS FROM `tb_anchor` [ RunTime:0.001053s ]
[ SQL ] SELECT * FROM `tb_anchor` ORDER BY `id` ASC [ RunTime:0.003022s ]
[ SQL ] SELECT `id`,`title` FROM `tb_tech` WHERE `id` > 863583 AND `check_status` = 1 AND `category_id` = 147 ORDER BY `submit_date` ASC LIMIT 1 [ RunTime:0.003686s ]
[ SQL ] SELECT `id`,`title` FROM `tb_tech` WHERE `id` < 863583 AND `check_status` = 1 AND `category_id` = 147 ORDER BY `submit_date` DESC LIMIT 1 [ RunTime:0.109136s ]
[ SQL ] select id,title,tag,submit_date from tb_tech where check_status=1 and id<>863583 order by submit_date desc limit 10 [ RunTime:0.003628s ]
[ SQL ] SHOW COLUMNS FROM `tb_mcc` [ RunTime:0.001200s ]
[ SQL ] SELECT * FROM `tb_mcc` WHERE `classify` = 1 [ RunTime:0.000971s ]
[ SQL ] SELECT * FROM `tb_mcc` WHERE `classify` = 2 [ RunTime:0.000942s ]
[ DB ] CONNECT:[ UseTime:0.001373s ] mysql:host=mccbfzy.mysql.polardb.rds.aliyuncs.com;port=3306;dbname=ysscdb;charset=utf8
[ SQL ] SHOW COLUMNS FROM `tb_industry_report` [ RunTime:0.001119s ]
[ SQL ] SELECT `id`,`cate_aid`,`cate_bid`,`title`,`pic`,`tag`,`price`,`hit`,`mode` FROM `tb_industry_report` [ RunTime:0.001245s ]
[ SQL ] SELECT * FROM `tb_category` WHERE `pid` = 36 ORDER BY `sortid` ASC [ RunTime:0.001065s ]
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[ SQL ] SELECT * FROM `tb_category` WHERE `pid` = 40 ORDER BY `sortid` ASC [ RunTime:0.000962s ]
[ SQL ] SELECT * FROM `tb_category` WHERE `pid` = 41 ORDER BY `sortid` ASC [ RunTime:0.000964s ]
[ SQL ] SHOW COLUMNS FROM `tb_advert` [ RunTime:0.001178s ]
[ SQL ] SELECT * FROM `tb_advert` WHERE `id` = 62 LIMIT 1 [ RunTime:0.000889s ]
[ SQL ] SELECT * FROM `tb_advert` WHERE `id` = 63 LIMIT 1 [ RunTime:0.000911s ]
[ SQL ] SELECT * FROM `tb_advert` WHERE `id` = 64 LIMIT 1 [ RunTime:0.000897s ]
[ SQL ] SELECT * FROM `tb_advert` WHERE `id` = 65 LIMIT 1 [ RunTime:0.000862s ]
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